diff --git a/python/packages/openai/agent_framework_openai/_chat_client.py b/python/packages/openai/agent_framework_openai/_chat_client.py
index 261554fba3..bf43b21e32 100644
--- a/python/packages/openai/agent_framework_openai/_chat_client.py
+++ b/python/packages/openai/agent_framework_openai/_chat_client.py
@@ -1454,10 +1454,21 @@ class RawOpenAIChatClient(  # type: ignore[misc]
         Returns:
             The prepared chat messages for a request.
         """
+        drops_reasoning_without_storage = not request_uses_service_side_storage and any(
+            content.type == "text_reasoning" for message in chat_messages for content in message.contents
+        )
+        drop_mcp_call_ids: set[str] = set()
+        if drops_reasoning_without_storage:
+            for message in chat_messages:
+                for content in message.contents:
+                    if content.type == "mcp_server_tool_call" and content.call_id:
+                        drop_mcp_call_ids.add(content.call_id)
+
         list_of_list = [
             self._prepare_message_for_openai(
                 message,
                 request_uses_service_side_storage=request_uses_service_side_storage,
+                drop_mcp_call_ids=drop_mcp_call_ids,
             )
             for message in chat_messages
         ]
@@ -1472,6 +1483,7 @@ class RawOpenAIChatClient(  # type: ignore[misc]
         message: Message,
         *,
         request_uses_service_side_storage: bool = True,
+        drop_mcp_call_ids: set[str] | None = None,
     ) -> list[dict[str, Any]]:
         """Prepare a chat message for the OpenAI Responses API format."""
         all_messages: list[dict[str, Any]] = []
@@ -1491,7 +1503,10 @@ class RawOpenAIChatClient(  # type: ignore[misc]
         # (replays_local_storage) still need stripping when the request also carries a continuation
         # marker, since the server-stored items would otherwise duplicate the inline ones. Without
         # storage, standalone reasoning items are invalid per the API ("reasoning was provided
-        # without its required following item"), so the reasoning branch always drops.
+        # without its required following item"), so the reasoning branch always drops. When that
+        # happens, `_prepare_messages_for_openai` also drops the paired hosted-MCP IDs across
+        # message boundaries rather than replaying bare MCP items.
+        drop_mcp_call_ids = drop_mcp_call_ids or set()
         for content in message.contents:
             match content.type:
                 case "text_reasoning":
@@ -1546,7 +1561,10 @@ class RawOpenAIChatClient(  # type: ignore[misc]
                     # server-side `id`, so under continuation it would duplicate
                     # the prior response's items (#3295). Drop the call here; the
                     # orphan result is dropped by the coalesce step that follows.
-                    if request_uses_service_side_storage:
+                    #
+                    # Without storage, a reasoning + hosted-MCP pair cannot be replayed
+                    # partially: reasoning is stripped above, and a bare mcp_call is rejected.
+                    if request_uses_service_side_storage or content.call_id in drop_mcp_call_ids:
                         continue
                     prepared_mcp = self._prepare_content_for_openai(
                         message.role,
diff --git a/python/packages/openai/tests/openai/test_openai_chat_client.py b/python/packages/openai/tests/openai/test_openai_chat_client.py
index e604742e7e..f02450a457 100644
--- a/python/packages/openai/tests/openai/test_openai_chat_client.py
+++ b/python/packages/openai/tests/openai/test_openai_chat_client.py
@@ -5648,6 +5648,79 @@ def test_prepare_messages_for_openai_coalesces_mcp_call_and_result_into_single_i
     assert fco_items == [], f"unexpected orphan function_call_output items: {fco_items}"
 
 
+def test_prepare_messages_for_openai_drops_mcp_call_when_paired_reasoning_is_stripped() -> None:
+    client = OpenAIChatClient(model="test-model", api_key="test-key")
+
+    messages = [
+        Message(
+            role="assistant",
+            contents=[
+                Content.from_text_reasoning(id="rs_abc123", text="Need the MCP server."),
+                Content.from_mcp_server_tool_call(
+                    call_id="mcp_abc123",
+                    tool_name="search",
+                    server_name="api_specs",
+                    arguments='{"q": "cats"}',
+                ),
+            ],
+        ),
+        Message(
+            role="tool",
+            contents=[
+                Content.from_mcp_server_tool_result(
+                    call_id="mcp_abc123",
+                    output=[Content.from_text(text="found 10 cats")],
+                )
+            ],
+        ),
+    ]
+
+    result = client._prepare_messages_for_openai(messages, request_uses_service_side_storage=False)
+
+    types = [item.get("type") for item in result if isinstance(item, dict)]
+    assert "reasoning" not in types
+    assert "mcp_call" not in types
+    assert "function_call_output" not in types
+
+
+def test_prepare_messages_for_openai_drops_mcp_call_across_reasoning_messages() -> None:
+    client = OpenAIChatClient(model="test-model", api_key="test-key")
+
+    messages = [
+        Message(
+            role="assistant",
+            contents=[Content.from_text_reasoning(id="rs_abc123", text="Need a tool call.")],
+        ),
+        Message(
+            role="assistant",
+            contents=[
+                Content.from_mcp_server_tool_call(
+                    call_id="mcp_abc123",
+                    tool_name="search",
+                    server_name="api_specs",
+                    arguments='{"q": "cats"}',
+                )
+            ],
+        ),
+        Message(
+            role="tool",
+            contents=[
+                Content.from_mcp_server_tool_result(
+                    call_id="mcp_abc123",
+                    output=[Content.from_text(text="found 10 cats")],
+                )
+            ],
+        ),
+    ]
+
+    result = client._prepare_messages_for_openai(messages, request_uses_service_side_storage=False)
+
+    types = [item.get("type") for item in result if isinstance(item, dict)]
+    assert "reasoning" not in types
+    assert "mcp_call" not in types
+    assert "function_call_output" not in types
+
+
 def test_prepare_messages_for_openai_drops_orphan_mcp_server_tool_result() -> None:
     """When an mcp_server_tool_result has no matching mcp_server_tool_call in
     the message list, it must be dropped, NOT serialized as a